GB Sciences has developed its proprietary GrowBLOX™ technology suite to control the growth of Cannabis and other plants with high medicinal value to a pharmaceutical-industry quality standard. The GrowBLOX™ system allows us to create “GBLX” branded, patented and certified therapeutic mixtures of raw plant ingredients through a comprehensive GBLX Quality Management Program. GB Sciences then acts as the central hub for testing the GBLX-certified materials in a technologically data-driven biopharmaceutical innovation system that aims to create and validate novel cannabis-based therapies for patients with clinically unmet needs.
Research Hypothesis
In order to treat specific disease categories with Cannabis-based products, we must correlate the profiles of active ingredients with symptom and disease-specific improvements.

These active ingredients include both cannabinoids and terpenes, which have been shown to be effective in the treatment of conditions including pain management, mood, metabolism, inflammation, cancer, neural and immune disorders.
What is a Profile of Active Ingredients?
For each individual Cannabis strain, we can measure the "profile" of active ingredients in the laboratory through analytical techniques that define the amounts and kinds of active molecules in that strain. The cannabinoid and terpenoid profiles of a representative strain are depicted here.
Cannabinoid
Terpenes
Assigning Cannabis strains to GBLX Targeted Treatment Categories
Based on an analysis of preclinical and clinical data from 1000's of peer-reviewed studies, GBLX has identified the most effective profiles of cannabinoids and terpenes for the treatment of conditions within seven GBLX Targeted Therapeutic Categories. We then classified natural Cannabis strains containing the ideal ratios for treating specific diseases, or symptoms within these GBLX Targeted Treatment Categories by performing a preliminary cluster analysis of the active ingredient profiles of 30,000 Cannabis strains in conjunction with a major testing lab.
GBLX Targeted Treatment Categories
Our scientists have identified optimum ratios of cannabinoids and terpenoids for the treatment of targeted disease categories and classified natural Cannabis strains that match the predicted ratios for the treatment of diseases in these provisional GBLX Targeted Treatment Categories. GB Sciences will use the GBLX-PRO smartphone app to validate the pre-selected strains or discover additional strains with defined cannabinoid/terpenoid ratios that are effective for the treatment of specific conditions.
Potential Market Value for GBLX Targeted Treatment Categories
01 | Cancer Treatments – $114 billion (2018)
02 | Cardioprotection – $187 billion (2018)
03 | Metabolic Syndrome $139.5 billion (2017)
04 | Pain Management – $29.47 billion (2018)
05 | Neurological Disorders – $952 billion (2018)
06 | Inflammation – $85.9 billion (2017)
07 | Compromised Immune System – $38 billion (2018)
GBLX Targeted Aliment Treatment

GBLX01 | Cancer Treatments

Targeted aliments:

Nausea

Appetite

Cancer growth

Nausea and vomiting are common side effects of many cancer treatments. Nausea is feeling the urge to vomit, or throw up. Vomiting may happen in expectation of treatment, within 24 hours after treatment, or two or more days after treatment.
Appetite fluctuation are common with cancer and cancer treatment. People with poor appetite or appetite loss may eat less than usual, not feel hungry at all, or feel full after eating only a small amount. Ongoing appetite loss may lead to weight loss, not getting the nutrients from food that the body needs, and loss of muscle mass and strength, all of which are serious complications. The combination of weight loss and muscle mass loss is called cachexia, or wasting.
Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors.  Tumors can grow and interfere with the digestive, nervous, and circulatory systems, and they can release hormones that alter body function.
Potential Market Value: 2018

GBLX02 | Cardioprotection

Targeted aliments:

Ischemi

Inflammation

Circulation

Ischemia is the medical term for what happens when your heart muscle doesn't get enough oxygen. Ischemia usually happens because of a shortage of blood and oxygen to the heart muscle. It is usually caused by a narrowing or blockage of one or more of the coronary arteries (which supply blood to the heart muscle).
Inflammation is part of the body's immune response. Initially, it is beneficial when, for example, your knee sustains a blow and tissues need care and protection. However, sometimes inflammation can cause further inflammation; it can become self-perpetuating. More inflammation is created in response to the existing inflammation.
Nothing slows you down quite like poor blood circulation does.  If you are not getting enough oxygen to your cells, in an effective and efficient way, then you’ll most likely feel sluggish, look worn and tired, and perhaps even be covering a more serious problem – one that could indicate cardiovascular disease.
Potential Market Value: 2018

GBLX03 | Metabolic Syndrome

Targeted aliments:

Blood sugar

Appetite

Out of control blood sugar levels can lead to serious short term problems such as hypoglycemia, hyperglycemia, or diabetic ketoacidosis. In the long run, uncontrolled blood sugar can also damage the vessels that supply blood to important organs, like the heart, kidneys, eyes, and nerves.
Changes in appetite are common with cancer and cancer treatment. People with poor appetite or appetite loss may eat less than usual, not feel hungry at all, or feel full after eating only a small amount. Ongoing appetite loss may lead to weight loss, not getting the nutrients from food that the body needs, and loss of muscle mass and strength, all of which are serious complications. The combination of weight loss and muscle mass loss is called cachexia, or wasting.
Potential Market Value: 2017

GBLX04 | Pain Management

Targeted aliments:

Acute pain

Inflammation pain

Chronic pain

This is some text inside of a div block.Acute pain begins suddenly and is usually sharp in quality. It serves as a warning of disease or a threat to the body. Acute pain might be caused by many events or circumstances.
Acute pain might be mild and last just a moment, or it might be severe and last for weeks or months. In most cases, acute pain does not last longer than six months, and it disappears when the underlying cause of pain has been treated or has healed.
When inflammation occurs, chemicals from the body's white blood cells are released into the blood or affected tissues to protect your body from foreign substances. This release of chemicals increases the blood flow to the area of injury or infection, and may result in redness and warmth. Some of the chemicals cause a leak of fluid into the tissues, resulting in swelling. This protective process may stimulate nerves and cause pain.
Chronic pain persists despite the fact that the injury has healed. Pain signals remain active in the nervous system for weeks, months, or years. Physical effects include tense muscles, limited mobility, a lack of energy, and changes in appetite. Emotional effects include depression, anger, anxiety, and fear of re-injury. Such a fear might hinder a person's ability to return to normal work or leisure activities.
Potential Market Value: 2018

GBLX05 | Neurological Disorders

Targeted aliments:

Insomnia

Anxiety

Spasms

Insomnia is a persistent disorder that can make it hard to fall asleep, hard to stay asleep or both, despite the opportunity for adequate sleep. With insomnia, you usually awaken feeling unrefreshed, which takes a toll on your ability to function during the day. Insomnia can sap not only your energy level and mood but also your health, work performance and quality of life.
Anxiety is an emotion characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure.People with anxiety disorders usually have recurring intrusive thoughts or concerns. They may avoid certain situations out of worry. They may also have physical symptoms such as sweating, trembling, dizziness or a rapid heartbeat.
A spasm is a sudden, involuntarycontraction of a muscle, a group of muscles,[1] or a hollow organ such as a heart, or a similarly sudden contraction of an orifice. It most commonly refers to a muscle cramp which is often accompanied by a sudden burst of pain, but is usually harmless and ceases after a few minutes.

Epileptic seizures

Psychosis

Depression

Epileptic seizure (colloquially a fit) is a brief episode of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain. The outward effect can vary from uncontrolled jerking movement (tonic-clonic seizure) to as subtle as a momentary loss of awareness (absence seizure). The disease of the brain characterized by an enduring predisposition to generate epileptic seizures is called epilepsy, but seizures can also occur in people who do not have epilepsy.
Psychosis refers to an abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People with psychosis are described aspsychotic. People experiencing psychosis may exhibit some personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depression, major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and depression may make you feel as if life isn't worth living.

Protect Nerves

A bundle of fibers composed of neurons that connects the body parts and organs to the central nervous system and carries impulses from one part of the body to another.
Potential Market Value: 2018

GBLX06 | Inflammation

Targeted aliments:

Gastritis

Psoriasis

Gastritis commonly refers to inflammation of the lining of the stomach, but the term is often used to cover a variety of symptoms resulting from stomach lining inflammation and symptoms of burning or discomfort.
Psoriasis, which affects at least four million Americans, is slightly more common in women than in men. Normal skin cells mature and replace dead skin every 28-30 days. Psoriasis causes skin cells to mature in less than a week. Because the body can't shed old skin as rapidly as new cells are rising to the surface, raised patches of dead skin develop on the arms, back, chest, elbows, legs, nails, folds between the buttocks, and scalp.
Potential Market Value: 2017

GBLX07 | Compromised Immune System

Targeted aliments:

Immunostimulant

Nausea

Wasting Syndrome

Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system by inducing activation or increasing activity of any of its components.
Nausea and vomiting are common side effects of many cancer treatments. Nausea is feeling the urge to vomit, or throw up. Vomiting may happen in expectation of treatment, within 24 hours after treatment, or two or more days after treatment.
A progressive involuntary weight loss seen in patients with HIV infection; may be due to a number of factors acting alone or in combination, including inadequate oral intake of food, altered metabolic state, and malabsorption.
Potential Market Value: 2018
GB Sciences has developed its proprietary GrowBLOX™ technology suite to control the growth of Cannabis and other plants with high medicinal value to a pharmaceutical-industry quality standard. The GrowBLOX™ system allows us to create “GBLX” branded, patented and certified therapeutic mixtures of raw plant ingredients through a comprehensive GBLX Quality Management Program. GB Sciences then acts as the central hub for testing the GBLX-certified materials in a technologically data-driven biopharmaceutical innovation system that aims to create and validate novel cannabis-based therapies for patients with clinically unmet needs.
Research Hypothesis
In order to treat specific disease categories with Cannabis-based products, we must correlate the profiles of active ingredients with symptom and disease-specific improvements.

These active ingredients include both cannabinoids and terpenes, which have been shown to be effective in the treatment of conditions including pain management, mood, metabolism, inflammation, cancer, neural and immune disorders.
What is a Profile of Active Ingredients?
For each individual Cannabis strain, we can measure the "profile" of active ingredients in the laboratory through analytical techniques that define the amounts and kinds of active molecules in that strain. The cannabinoid and terpenoid profiles of a representative strain are depicted here.
Cannabinoid
Terpenes
Assigning Cannabis strains to GBLX Targeted Treatment Categories
Based on an analysis of preclinical and clinical data from 1000's of peer-reviewed studies, GBLX has identified the most effective profiles of cannabinoids and terpenes for the treatment of conditions within seven GBLX Targeted Therapeutic Categories. We then classified natural Cannabis strains containing the ideal ratios for treating specific diseases, or symptoms within these GBLX Targeted Treatment Categories by performing a preliminary cluster analysis of the active ingredient profiles of 30,000 Cannabis strains in conjunction with a major testing lab.
GBLX Targeted Treatment Categories
Our scientists have identified optimum ratios of cannabinoids and terpenoids for the treatment of targeted disease categories and classified natural Cannabis strains that match the predicted ratios for the treatment of diseases in these provisional GBLX Targeted Treatment Categories. GB Sciences will use the GBLX-PRO smartphone app to validate the pre-selected strains or discover additional strains with defined cannabinoid/terpenoid ratios that are effective for the treatment of specific conditions.
Potential Market Value for GBLX Targeted Treatment Categories
01 | Cancer Treatments – $114 billion (2018)
02 | Cardioprotection – $187 billion (2018)
03 | Metabolic Syndrome $139.5 billion (2017)
04 | Pain Management – $29.47 billion (2018)
05 | Neurological Disorders – $952 billion (2018)
06 | Inflammation – $85.9 billion (2017)
07 | Compromised Immune System – $38 billion (2018)
GBLX Targeted Aliment Treatment

GBLX01 | Cancer Treatments

Targeted aliments:

Nausea

Appetite

Cancer growth

Nausea and vomiting are common side effects of many cancer treatments. Nausea is feeling the urge to vomit, or throw up. Vomiting may happen in expectation of treatment, within 24 hours after treatment, or two or more days after treatment.
Appetite fluctuation are common with cancer and cancer treatment. People with poor appetite or appetite loss may eat less than usual, not feel hungry at all, or feel full after eating only a small amount. Ongoing appetite loss may lead to weight loss, not getting the nutrients from food that the body needs, and loss of muscle mass and strength, all of which are serious complications. The combination of weight loss and muscle mass loss is called cachexia, or wasting.
Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors.  Tumors can grow and interfere with the digestive, nervous, and circulatory systems, and they can release hormones that alter body function.
Potential Market Value: 2018

GBLX02 | Cardioprotection

Targeted aliments:

Ischemia

Inflammation

Circulation

Ischemia is the medical term for what happens when your heart muscle doesn't get enough oxygen. Ischemia usually happens because of a shortage of blood and oxygen to the heart muscle. It is usually caused by a narrowing or blockage of one or more of the coronary arteries (which supply blood to the heart muscle).
Inflammation is part of the body's immune response. Initially, it is beneficial when, for example, your knee sustains a blow and tissues need care and protection. However, sometimes inflammation can cause further inflammation; it can become self-perpetuating. More inflammation is created in response to the existing inflammation.
Nothing slows you down quite like poor blood circulation does.  If you are not getting enough oxygen to your cells, in an effective and efficient way, then you’ll most likely feel sluggish, look worn and tired, and perhaps even be covering a more serious problem – one that could indicate cardiovascular disease.
Potential Market Value: 2018

GBLX03 | Metabolic Syndrome

Targeted aliments:

Blood sugar

Appetite

Out of control blood sugar levels can lead to serious short term problems such as hypoglycemia, hyperglycemia, or diabetic ketoacidosis. In the long run, uncontrolled blood sugar can also damage the vessels that supply blood to important organs, like the heart, kidneys, eyes, and nerves.
Changes in appetite are common with cancer and cancer treatment. People with poor appetite or appetite loss may eat less than usual, not feel hungry at all, or feel full after eating only a small amount. Ongoing appetite loss may lead to weight loss, not getting the nutrients from food that the body needs, and loss of muscle mass and strength, all of which are serious complications. The combination of weight loss and muscle mass loss is called cachexia, or wasting.
Potential Market Value: 2017

GBLX04 | Pain Management

Targeted aliments:

Acute pain

Inflammation pain

Chronic pain

This is some text inside of a div block.Acute pain begins suddenly and is usually sharp in quality. It serves as a warning of disease or a threat to the body. Acute pain might be caused by many events or circumstances.
Acute pain might be mild and last just a moment, or it might be severe and last for weeks or months. In most cases, acute pain does not last longer than six months, and it disappears when the underlying cause of pain has been treated or has healed.
When inflammation occurs, chemicals from the body's white blood cells are released into the blood or affected tissues to protect your body from foreign substances. This release of chemicals increases the blood flow to the area of injury or infection, and may result in redness and warmth. Some of the chemicals cause a leak of fluid into the tissues, resulting in swelling. This protective process may stimulate nerves and cause pain.
Chronic pain persists despite the fact that the injury has healed. Pain signals remain active in the nervous system for weeks, months, or years. Physical effects include tense muscles, limited mobility, a lack of energy, and changes in appetite. Emotional effects include depression, anger, anxiety, and fear of re-injury. Such a fear might hinder a person's ability to return to normal work or leisure activities.
Potential Market Value: 2018

GBLX05 | Neurological Disorders

Targeted aliments:

Insomnia

Anxiety

Spasms

Insomnia is a persistent disorder that can make it hard to fall asleep, hard to stay asleep or both, despite the opportunity for adequate sleep. With insomnia, you usually awaken feeling unrefreshed, which takes a toll on your ability to function during the day. Insomnia can sap not only your energy level and mood but also your health, work performance and quality of life.
Anxiety is an emotion characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure.People with anxiety disorders usually have recurring intrusive thoughts or concerns. They may avoid certain situations out of worry. They may also have physical symptoms such as sweating, trembling, dizziness or a rapid heartbeat.
A spasm is a sudden, involuntarycontraction of a muscle, a group of muscles,[1] or a hollow organ such as a heart, or a similarly sudden contraction of an orifice. It most commonly refers to a muscle cramp which is often accompanied by a sudden burst of pain, but is usually harmless and ceases after a few minutes.

Epileptic seizures

Psychosis

Depression

Epileptic seizure (colloquially a fit) is a brief episode of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain. The outward effect can vary from uncontrolled jerking movement (tonic-clonic seizure) to as subtle as a momentary loss of awareness (absence seizure). The disease of the brain characterized by an enduring predisposition to generate epileptic seizures is called epilepsy, but seizures can also occur in people who do not have epilepsy.
Psychosis refers to an abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People with psychosis are described aspsychotic. People experiencing psychosis may exhibit some personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depression, major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and depression may make you feel as if life isn't worth living.

Protect Nerves

A bundle of fibers composed of neurons that connects the body parts and organs to the central nervous system and carries impulses from one part of the body to another.
Potential Market Value: 2018

GBLX06 | Inflammation

Targeted aliments:

Gastritis

Psoriasis

Gastritis commonly refers to inflammation of the lining of the stomach, but the term is often used to cover a variety of symptoms resulting from stomach lining inflammation and symptoms of burning or discomfort.
Psoriasis, which affects at least four million Americans, is slightly more common in women than in men. Normal skin cells mature and replace dead skin every 28-30 days. Psoriasis causes skin cells to mature in less than a week. Because the body can't shed old skin as rapidly as new cells are rising to the surface, raised patches of dead skin develop on the arms, back, chest, elbows, legs, nails, folds between the buttocks, and scalp.
Potential Market Value: 2017

GBLX07 | Compromised Immune System

Targeted aliments:

Immunostimulant

Nausea

Wasting Syndrome

Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system by inducing activation or increasing activity of any of its components.
Nausea and vomiting are common side effects of many cancer treatments. Nausea is feeling the urge to vomit, or throw up. Vomiting may happen in expectation of treatment, within 24 hours after treatment, or two or more days after treatment.
A progressive involuntary weight loss seen in patients with HIV infection; may be due to a number of factors acting alone or in combination, including inadequate oral intake of food, altered metabolic state, and malabsorption.
Potential Market Value: 2018
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